Autonomous Agents: Artists on Human-Machine Interaction captures a pivotal moment in AI’s impact on art and society through interviews with fifteen artists spanning diverse geographies, generations, and philosophies. As machines’ ability to generate complex imagery and advancements in autonomous agents have increased at an exponential rate, artists’ voices are often lost in the unrelenting cacophony of novelty. Sol LeWitt’s 1967 declaration, “the idea becomes a machine that makes the art,” offers advice for the present moment, where the boundaries between art and technology are increasingly porous. This collection takes stock of this vertiginous moment from their point of view, featuring practices that engage advanced technologies in meaningful, nuanced, and critically challenging ways.